AUTHORS: Ginami G, Yerly J, Masci PG, Stuber M

Magnetic Resonance in Medicine, 77(3): 961-969, March 2017

ABSTRACT

Purpose: 

The need for performing dual-inversion recovery (DIR) coronary vessel wall MRI in correspondence to minimal cardiac motion and optimal blood signal nulling is a major challenge. We propose to address this hurdle by combining DIR with a prolonged acquisition window in conjunction with a golden angle radial trajectory and k-t sparse sensitivity encoding (SENSE) reconstruction to enable a flexible a-posteriori selection of optimized imaging parameters.

Methods: 

Coronary vessel wall data acquisition was performed with DIR golden angle radial imaging in n=15 healthy subjects. Images reconstructed using k-t sparse SENSE and different reconstruction window settings were quantitatively (vessel wall conspicuity, thickness, acquisition, and reconstruction window settings) compared with those obtained with more conventional radial DIR imaging.

Results: 

A flexible retrospective selection of the reconstruction window width and position improved vessel wall conspicuity with respect to baseline acquisitions (P < 0.01). Vessel wall thickness remained unchanged (P = nonsignificant (NS)). Temporal window widths were similar for both approaches (P = NS), yet their position within the cardiac cycle differed significantly (P < 0.02).

Conclusions: 

A flexible DIR coronary vessel wall MRI technique that alleviates constraints associated with sophisticated sequence timing was proposed. When compared with a more conventional approach, the technique significantly improved image quality.

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